Picking Monday Night Football best bets week after week is a tough task, but our team is here to help. The Sports Geek will review hundreds of markets available each Monday, delivering expert MNF betting picks for player props, team props, and traditional markets like totals, spreads, and moneylines.
Check this page regularly for the latest picks and tips the team at The Sports Geek has prepared for this week. For Week 17, the Detroit Lions travel to the Bay Area for a primetime showdown versus the San Francisco 49ers. Here are our best bets for the Monday Night Football Week 17 Lions vs. 49ers matchup:
MNF Best Bets This Week: Lions vs. 49ers
BEST BET | ODDS | BOOKMAKER |
---|---|---|
Detroit Lions -3 | -125 | BetOnline |
Total Points in Game: 51-60 | +230 | BetOnline |
Race to 10: Detroit Lions | -152 | Bovada |
Anytime TD: Sam LaPorta | +200 | Bovada |
Receiving Yards: Jahmyr Gibbs (DET) Over 27.5 | -115 | Bovada |
Longest Reception: Amon-Ra St. Brown (DET) Over 21.5 | -120 | Bovada |
Parlay: LaPorta TD; Gibbs Over 27.5 Rec. Yds; St. Brown Longest Recp. | +928 | Bovada |
Monday Night Football Odds and Betting Lions for Week 17: Lions vs. 49ers
Online betting sites have a variety of Monday Night Football bets available for the Detroit Lions (13-2) vs. San Francisco 49ers (6-9) Week 17 matchup. The main markets, including the point spread, are on the board at most major sportsbooks.
Let’s delve into the Lions vs. 49ers lines and best Thursday Night Football bets below!
The following MNF odds are courtesy of BetOnline:
TEAM | SPREAD | MONEYLINE | TOTAL |
---|---|---|---|
Detroit Lions -3 | -125 | -175 | Over 50.5 (-110) |
San Francisco 49ers +3 | +105 | +115 | Under 50.5 (-110) |
The Detroit Lions are three-point favorites to defeat the 49ers on the West Coast this week. At -175 on the moneyline, the Lions are favored to win with a 63.6% implied probability!
The 49ers are statistically out of the playoff picture, but NFL betting sites expect them to be competitive against the 13-win Lions. Also, according to the over/under, oddsmakers see this matchup turning into a shootout.
If you are interested in alternative lines and other unique MNF prop bets tonight, Bovada has a wide selection of options. You can find the most up-to-date MNF betting odds at Bovada by navigating to All Sports > Football > NFL > Detroit Lions vs. San Francisco 49ers.
Monday Night Football Betting Trends
There are some key betting trends to keep in mind before placing your best Monday Night Football bets!
I’ve dug through several trends for this matchup and have isolated the best to consider for the Lions vs. 49ers:
- The Detroit Lions are 10-5-0 against the spread (ATS) in 2024.
- The Detroit Lions are 4-1 against the spread (ATS) in their previous five games versus the San Francisco 49ers.
- The Detroit Lions are 7-0 outright in their previous seven games on the road.
- The Detroit Lions are 5-1-0 against the spread (ATS) in their previous six games as a road favorite.
- The Detroit Lions are 7-3-0 against the spread (ATS) in their previous ten games in non-NFC North games.
- The San Francisco 49ers are 5-10 against the spread (ATS) in 2024.
- The San Francisco 49ers are 1-6 against the spread (ATS) in their previous seven games.
- The San Francisco 49ers are 4-11 against the spread (ATS) in their previous 15 games at home.
- The over is 8-4 in the Detroit Lions’ previous 12 games overall.
- The over is 4-1 in the previous five meetings between the Detroit Lions and San Francisco 49ers.
MNF Football Prediction and Betting Pick: Lions vs. 49ers
The Detroit Lions have their eyes set on the No. 1 seed for the NFC Championship. With a victory over the 49ers, the Lions can inch closer to guaranteeing homefield advantage through the playoffs. Next week, the Lions can clinch the NFC North title against the Minnesota Vikings.
The Lions have fallen victim to the injury bug hard this season. While other contenders, such as the Kansas City Chiefs are in the process of getting healthy, the Lions are reeling with injuries.
That said, this team is so well-coached on both sides of the ball that the Lions can go down the depth chart and get results. The banged-up Lions are coming off a 34-17 victory over the Chicago Bears on the road.
Safety Brian Branch and CB Terrion Arnold made big plays against Bears’ QB Caleb Williams and the offense. If Arnold, Branch, and LB Jack Campbell can stay on the field, defensive coordinator Aaron Glenn will draw something up to slow down the 49ers.
The 49ers have regressed offensively without a healthy RB Christian McCaffrey in the mix. They are 16th in the NFL, with an average of 22.1 points scored per game.
Finishing drives has proven to be an issue, as just 51.79% of red zone trips have resulted in a touchdown. The defense has been in fine shape, but they are dealing with a high-powered Lions’ offense that isn’t injured enough to be hampered.
Lions’ QB Jared Goff is an outsider for NFL MVP, but he has to be behind Lamar Jackson and Josh Allen in the conversation. Goff has passed for 17 touchdowns and one interception over the last seven weeks! With second-year WR Jameson Williams breaking out, Goff has an array of weapons in an explosive offense.
Matched with Pro Bowl WR Amon-Ra St. Brown and RB Jahmyr Gibbs, injuries aren’t so much of a concern on the offensive side of the ball. The offensive line has kept Goff up-right with 1.9 sacks yielded per game — tied for the seventh-best mark.
Although I’m concerned with the Lions winning shootouts against elite offenses, the 49ers don’t have the horses to keep up in this one. The Lions are first in the NFL, averaging 32.9 points, and second with 408.6 yards per game!
We’re getting a short number due to the injury concerns and this game being largely meaningless for Detroit, but the 49ers have checked out and aren’t a threat to exploit the Lions’ holes. Head coach Dan Campbell won’t allow this team slump on Monday night. There is betting value on the Lions at -3, so consider laying the points!
Team MNF Prop Bets: Lions vs. 49ers
Leading online bookmaker Bovada has a variety of Monday Night Football prop bets for the Lions vs. 49ers. Let’s delve into my top team props this week:
Total Points in Game: 51-60 (+230)
- 41-50 Points: +210
- 51-60: +230
- 31-40: +425
- 61-70: +450
- 71+: +800
- 21-30: +1200
- 0-20: +5000
Points shouldn’t be tough to come by on Monday Night Football this week. Goff and the Lions will come out firing looking to give the injured defense some support. The Lions have the personnel to pull off this game plan, so expect Goff to get to work right away on their first possession.
The injuries turn the Lions into a good defense to average. As I said, the Lions still have defensive players remaining to play a respectable game under Glenn’s scheme. However, the offense will overwhelmingly be the catalyst through January. In short, I have the Lions down for 30 points at Levi’s Stadium in the Bay Area.
The 49ers will attempt to keep up, but should come up shy of Goff and Co. Look for San Francisco to bank 24 points, so a 30-24 final, and 51-60 points is the most likely outcome for your Week 17 MNF props!
Race to 10 Points: Detroit Lions (-152)
- Detroit Lions (-152)
- San Francisco 49ers (+115)
- Neither (+10000)
To reiterate, I expect the Lions to get off to a fast start with Goff. The Lions’ coaching staff won’t be hesitant to attempt to pull ahead early to afford their defense a cushion. The Lions lead the league, with an average of 18.7 points scored per first half.
They are accustomed to putting points on the board and getting out to comfortable leads early. Conversely, the 49ers are 17th in the NFL, with 11.5 points scored per game in the first half. Look for San Francisco to concede a couple of quick touchdowns to get behind at home.
With this in mind, the Lions should win the race to 10 points! Consider adding this wager to your best MNF prop bets this week.
Best Monday Night Football Player Props This Week
Now, let’s delve into the best MNF player prop bets to consider locking in at sports betting apps and sites for the Lions vs. 49ersThere is a trio of appealing anytime touchdown bets, so let’s analyze these best Monday Night Football player props this week on Bovada below:
Anytime Touchdown: (DET) Sam LaPorta (+200)
Lions’ sophomore TE Sam LaPorta has been a valuable weapon for the Lions, especially in the red zone when Goff is looking for a reliable option. LaPorta has caught 68 receptions for 599 yards and six touchdowns.
He has reeled in three of his touchdowns over the last four games. During that stretch, LaPorta has been targeted 30 times, plenty of which have been in the end zone. LaPorta is often the first read for Goff in the red zone, so he has an enchanted chance to score.
For your Week 17 MNF player prop bets, LaPorta’s anytime touchdown wager at +200 is a top-flight option against the 49ers!
Total Receiving Yards: Jahmyr Gibbs (DET) Over 27.5 (-115)
- Over 27.5 Yards (-115)
- Under 27.5 Yards (-115)
Lions’ RB Jahmyr Gibbs has developed into the centerpiece of the offense in Detroit. He runs the ball, blocks, and is used as a pass catcher out of the backfield. Gibbs can even be spread out in a receiver set for the Lions. In short, Gibbs’ receiving prop is roughly five or six years too low.
Gibbs has collected 43 receptions, 440 yards, and three touchdowns in the passing game. Through the last three weeks, Gibbs was used frequently as a receiver. He hauled in 15 receptions for 158 yards — eclipsing 30 yards in each matchup.
The former Alabama running back’s receiving prop to go over 27.5 is a solid option for your MNF player prop bets!
Longest Reception: Amon-Ra St. Brown (DET) Over 21.5
- Over 21.5 Yards (-120)
- Under 21.5 Yards (-110)
As I mentioned, the Lions will come out of the gate attacking the 49ers’ defense looking to land an early blow. WR Amon-Ra St. Brown is his top receiving target, and often looks to the USC product downfield.
It doesn’t matter where St. Brown is on the field, as he is terrific across the middle on short routes or stretching the secondary. St. Brown is a versatile weapon that the Lions couldn’t afford to lose to an injury. He enters this week with 101 receptions, 1,126 yards, and 11 touchdowns.
The 25-year-old California native has a season-long reception of 66 yards. He has surpassed the 21-yard threshold in three of his previous four games. St. Brown has also gone beyond this mark in four of the last five matchups.
With the Lions looking to send a message early, expect St. Brown to see plenty of targets downfield. St. Brown’s longest reception prop of over 21.5 yards is worth considering for your MNF player props this week!
Monday Night Football Parlay for Week 17
For my final Monday Night Football betting pick, I am wrapping up my card with a parlay bet that includes all three of the abovementioned props. In short, the best MNF parlay for my card is LaPorta anytime TD, Gibbs over 27.5 receiving yards, and St. Brown over 21.5 longest reception at Levi’s Stadium.
On a $100 wager, bettors can bank $928.26 at +928 odds with a winning ticket! Considering this monster payout, it’s certainly a wager that should be on your radar for your NFL betting strategy this week.
For more NFL Week 17 picks, check out our exclusive A.I. football bets this week. Also, we recommend entering The Sports Geek’s FREE NFL pick’em contest for a chance at Amazon gift cards in Week 17 and the rest of the season.
- LaPorta: Anytime TD
- Gibbs: Over 27.5 Receiving Yards
- St. Brown: Over 21.5 Longest Reception
Monday Night Football Summary: Lions vs. 49ers
The Sports Geek is excited to conclude the Week 17 NFL betting card with our best Monday Night Football bets for the Lions vs. 49ers! While we can’t promise that you’ll become as wealthy as the richest NFL owners, there is big cash to be won on the gridiron this season.
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