NFL 2024 Week 10 Betting Odds and Lines

The NFL Week 10 odds and betting lines feature multiple divisional matchups and close games, so the week should be a feast for all football fans!

Let’s explore the latest betting odds together and see where the value lies for all matchups on the Week 10 NFL schedule.

NFL Week 10 Schedule (2024)

Top football betting sites have competitive odds on every game this week. Here is the full schedule for Week 10 of the 2024 NFL season.

Four teams, the Browns, Packers, Raiders, and Seahawks, are on a bye this week. The NFL Week 10, 2024 schedule opens with an AFC North battle between the Bengals and the Ravens on Thursday Night Football.

Here are the latest NFL Week 10 odds, courtesy of Bovada.

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Cincinnati Bengals vs. Baltimore Ravens Odds and Best Bets

Week 10 kicks off with a rematch of one of the best games of the first half of the season. Baltimore defeated Cincinnati 41-38 in overtime in their Week 5 matchup. The Ravens are 5.5-point favorites this week as they host the Bengals on Thursday Night Football.

The Ravens (6-3) have a chance to retake control of the AFC North with a win this week. Cincinnati (4-5), on the other hand, needs a win to get back to .500 and keep its playoff hopes alive. The Bengals’ defense failed Cincinnati when these teams played in Week 5, and I think it will be their fatal flaw again this week.

Baltimore has scored at least 28 points in seven straight games, including 41 points in three of its previous five games. Lamar Jackson and company should have another high-scoring game despite it being a short week. The Ravens should win, but I think the Bengals will cover on TNF this week.

New York Giants vs. Carolina Panthers Odds and Best Bets

Sunday’s slate of games for Week 10 starts with a matchup between the Giants (2-7) and Panthers (2-7) in Munich, Germany. These teams are a combined 4-14, but one of them has to win this game. The Giants are the 5-point betting favorite in the latest NFL odds for Week 10.

Carolina upset the New Orleans Saints last week for its second win of the season. The Panthers will face a much tougher matchup this week against a Giants’ defense that features Dexter Lawrence. He has nine sacks this season, which is second-most in the NFL.

For comparison, the Panthers have 10 sacks as a team, tied for the second-fewest on the season. New York also has Tyrone Tracy and Malik Nabers, two of the top rookie offensive players this season. The Giants should win this matchup, but I don’t expect a big margin.

New England Patriots vs. Chicago Bears Odds and Best Bets

The Patriots and the Bears both lost last week, and their playoff hopes are hanging in the balance. New England (2-7) must win out to have any chance of making the postseason. Chicago (4-4) has lost back-to-back games and is eighth in the NFC.

Bovada has Chicago as a 6.5-point favorite in its Week 10 NFL odds. The Bears are playing at home for the first time in a month and need to win this game. Their defense looked terrible against Arizona, allowing 213 rushing yards in their 29-9 loss.

Chicago’s offense has also struggled in the last two weeks, and Mike Eberflus could be coaching for his job. The Bears have plenty of motivation and should win this game. However, Drake Maye and the Patriots offense will keep this matchup competitive and cover the 6.5-point spread.

Buffalo Bills vs. Indianapolis Colts Odds and Best Bets

Buffalo (7-2) has blown away the rest of the AFC East this season and can move one step closer to a divisional title with a win this week. The Bills are 4-point road favorites over the Colts in the NFL football odds for this Week 10 matchup.

Indianapolis lost on Sunday Night Football to the Vikings in Week 9. Joe Flacco was unable to recreate his magic earlier in the season, finishing with just 16 completions for 179 yards and an interception in the 21-13 loss.

The Colts best chance to win this game is to lean heavily on Jonathan Taylor. Buffalo has allowed 4.8 yards per carry to opposing rushers, tied for sixth-most in the NFL.  The Bills have scored at least 30 points in three straight games, and even with a great game from Taylor, I doubt the Colts can cover their spread on Sunday.

Minnesota Vikings vs. Jacksonville Jaguars Odds and Best Bets

Speaking of Minnesota, the Vikings are a 3.5-point favorite in the latest NFL line for their Week 10 matchup against the Jaguars. Jacksonville (2-7) is arguably the most disappointing team of the season, and their next loss could be Doug Pederson’s last game as their head coach.

The Vikings’ win over the Colts on SNF ended Minnesota’s two-game losing streak. However, Sam Darnold and company still need a win this week to keep pace with Detroit (7-1). Star tight end T.J. Hockenson returned to the lineup last week, reeling in three catches for 27 yards in his season debut.

With Hockenson healthy again, the Vikings’ offense should have a field day against the Jaguars. Jacksonville has allowed 2.502 passing yards this season, the second-most in the NFL. This game is in Jacksonville, but the Vikings should win and cover this weekend.

Denver Broncos vs. Kansas City Chiefs Odds and Best Bets

Denver (5-4) had a chance to make a statement last week in its game against Baltimore. The Broncos could have announced themselves as a playoff contender, but the opposite happened. Denver is an 8-point underdog in Kansas City this week after the 41-10 loss to the Ravens.

The Chiefs are listed at -400 to win this game outright in the latest NFL Week 10 lines. Kansas City will most likely win, but I think the Broncos can cover the spread this weekend.

Patrick Mahomes and the Chiefs offense have struggled to move the ball this season, and the injuries to their skill players have not helped. Kansas City needed overtime to beat the Buccaneers, who have one of the worst passing defenses in the league. I believe Denver will keep this game close and cover the 8-point spread.

Atlanta Falcons vs. New Orleans Saints Odds and Best Bets

The Saints fired their head coach, Dennis Allen, following their 23-22 loss to Carolina on Sunday. New Orleans also traded away Marshon Lattimore, one of its best defensive players, on Tuesday. The Saints are a 3.5-point underdog at home with NFC South leader Atlanta coming to town.

Atlanta has yet to lose a divisional game this season, and with a win this week, they can improve to 4-0 in the South. New Orleans, conversely, has lost seven games in a row. That includes a 26-24 defeat against Atlanta in Week 4.

The Falcons could be without Drake London after the receiver suffered a hip injury on Sunday. Even if London misses this game, the Falcons have plenty of firepower to overwhelm the Saints. Atlanta are the most likely winners here and should cover the 3.5-point spread.

San Francisco 49ers vs. Tampa Bay Buccaneers Odds and Best Bets

The only team with a realistic chance to catch the Falcons in the NFC South is Tampa Bay. Questionable coaching decisions cost the Buccaneers last week, and they lost 30-24 in overtime to the Chiefs.

Now, Tampa Bay is a 5.5-point home underdog against San Francisco in the updated NFL spreads for Week 10.

San Francisco (4-4) is coming off its bye, and star running back Christian McCaffrey is expected to make his season debut. Having CMC back in the lineup will make it much easier for the 49ers to hide their other deficiencies on offense. Tampa Bay has also allowed 5 YPC, which is tied for the fourth-most in the NFL.

I am confident about the 49ers winning this game, but San Francisco has not been good at covering the spread this season. They are just 4-4 ATS, and their losses to the Rams and Cardinals both came via late-game comebacks. San Fran will win, but the 49ers will not cover the spread this week.

Pittsburgh Steelers vs. Washington Commanders Odds and Best Bets

Pittsburgh and Washington were both active at the season’s trade deadline ahead of their Week 10 matchup. Washington added Marshon Lattimore, a four-time Pro Bowl DB, while Pittsburgh traded for Mike Williams, a 30-year-old receiver with just 12 catches this year.

The Steelers also traded for pass rusher Preston Smith, but that will not be enough to overcome the Commanders on Sunday. Washington is a 3-point home favorite in Bovada’s NFL Week 10 projections. The Commanders have been rolling this season with Rookie of the Year favorite Jayden Daniels at quarterback.

Daniels is likely to have a great day at the office Sunday and help the Commanders will pick up the win. Pittsburgh has a good run defense on paper, but they were gashed by Tyrone Tracy (150 total yards), Rico Dowdle (114 total yards), and Breece Hall (141 total yards) in recent weeks. The Commanders have one of the top rushing attacks in the NFL, and they will run all over the Steelers while covering the 3-point spread.

Tennessee Titans vs. Los Angeles Chargers Odds and Best Bets

Tennessee won in overtime against New England last week to improve to 2-6 on the season. The Titans are 7.5-point road underdogs in the latest NFL spreads for their Week 10 matchup against the Chargers. Tennessee has only scored 21 or more points once this season, and the Chargers have done it three times in their last four games.

LA’s passing attack has improved in recent weeks, which is bad news for the Titans. In the last two games, Justin Herbert has completed 64.4% of his passes for 561 yards and four touchdowns. He also has not thrown a pick since Week 2.

Tennessee’s defense will not be able to stop the Chargers. The Titans have held the Patriots to 17 points, but they allowed 52 to Detroit and 34 to the Bills. LA also has the best scoring defense in the league and should cover the spread on Sunday.

New York Jets vs. Arizona Cardinals Odds and Best Bets

Aaron Rodgers and the Jets pulled off the upset win on TNF against the Texans last week. Now, New York (3-6) must travel to the desert to face the Cardinals (5-4) in Arizona. The Cardinals have won three straight games and are 1-point favorites in Bovada’s NFL Week 10 spreads.

Both teams have struggled to stop the run this season. Arizona has allowed 1,196 rushing yards, the ninth-most in the league. New York has allowed the 10th-most (1,193) and has surrendered 11 rushing touchdowns to Arizona’s 10.

A run-heavy game will favor the Cardinals, who have amassed 1,347 rushing yards this year, the fifth-most in the league. Arizona also averages 5/3 YPC, which is the second-highest in the NFL. I think Arizona will win this game and cover the 1-point spread.

Philadelphia Eagles vs. Dallas Cowboys Odds and Best Bets

The second and third-ranked teams in the NFC East face off this weekend with the Eagles traveling to Texas to face the Cowboys. Philadelphia is a 7.5-point road favorite in Bovada’s NFL betting lines for Week 10.

Dallas placed starting quarterback Dak Prescott on IR with a hamstring injury he suffered in the team’s Week 9 loss in Atlanta. CeeDee Lamb was also injured in the game and is questionable with a sprained AC joint. Philadelphia’s A.J. Brown was injured as well and could miss the game with a knee injury.

Even without Brown, the Eagles should easily win this game. Dallas has been blown out in every home game this year and will be without their only two good offensive players. Philly wins and covers in this NFC East matchup.

Detroit Lions vs. Houston Texans Odds and Best Bets

This should be a good one, with the Lions (7-1) and Texans (6-3) fighting in Sunday Night Football for Week 10. Detroit has rolled their recent opponents and are 3.5-point road favorites in Bovada’s NFL odds for Week 10, 2024. Houston lost the Jets last week and is 0-2 against the NFC North this season.

Jared Goff and the Lions have won six straight games, scoring at least 20 points in every game over that stretch. Goff has shot up MVP odds boards and leads the NFL in completion percentage (74.9%) among passers with 30 or more attempts. He should have another productive day against a Texans team that has allowed a league-high 19 passing touchdowns this season.

Detroit is exceeding expectations this year, and the Texans are starting to crumble under them. Without its two best wide receivers, Houston struggled to move the ball against the Jets. Stefon Diggs and Nico Collins are out again this week, and I think the Texans’ issues will continue in a losing effort this week.

Miami Dolphins vs. Los Angeles Rams Odds and Best Bets

Rounding out the NFL Week 10 betting odds is a Monday Night Football matchup between the Dolphins (2-6) and the Rams (4-4). Tua Tagovailoa returned to the lineup two weeks ago, but the Dolphins are still searching for their first win since Week 5.

The Rams are 2.5-point home favorites in the updated Week 10, 2024 NFL odds. Miami’s offense has struggled this season, while LA’s has been rolling since the returns of Cooper Kupp and Puka Nacua. However, despite their recent performances, I think the Dolphins can pull off the upset this week.

LA has allowed 15 passing touchdowns, tied for the sixth-most, and Miami has allowed just eight, tied for the fifth-fewest. The Dolphins have also given up the 10th-fewest rushing yards (960) this season. Miami is desperate for a win, so I expect the best of them on Monday.

Where to Find the Best NFL Betting Lines for Week 10

The opening NFL Week 10 betting odds from Bovada Sportsbook are a great way to wager on your favorite teams this week. You can find the latest odds and my best bets for this week in the guide above.

I also recommend checking our free Beat the Geek contest that offers fantastic prizes, including three Amazon gift cards worth $100 each every week.