NFL Week 13 Odds and Lines: Who Will Feast on Thanksgiving Weekend?

The NFL Week 13 odds feature three Thanksgiving games, a Black Friday game, and 12 other exciting matchups. With the regular season quickly winding down, teams are battling for their spots in the postseason.

All 32 NFL teams are in action this week, so the NFL odds for Week 13 have great betting opportunities for every NFL fan. This guide will break down the moneyline, point spread, and point total odds for every game. I will also highlight my best bets for every Week 13 game.

NFL Week 13 Schedule

Top NFL betting sites offer competitive odds on all 16 games on this week’s schedule. Refer to the table below to see every game on the NFL Week 13 schedule.

Bovada has thrilling betting markets for every game above, including the Thanksgiving tripleheader and the stand-alone Black Friday game.

Here are the latest Week 13 NFL odds and my best bets for every game this week.

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Chicago Bears vs. Detroit Lions Odds and Best Bets

This year’s Thanksgiving tripleheader opens with an NFC North matchup between the Bears (4-7) and the Lions (10-1). Detroit is a 10.5-point favorite in the earlier NFL football odds for Week 13. The Lions are riding a nine-game winning streak, and Chicago has lost five in a row.

Detroit is a worthy favorite at home, but they have stumbled in big spots in the past. The Lions lost 29-22 to the then-4–6 Packers at home last Thanksgiving. Detroit also barely overcame a five-interception game from Jared Goff against the Texans in Week 11 in their last prime-time appearance.

This game is not in prime time, but it is a holiday game, and the Bears have a defense that can get after Goff. Chicago has also lost its last two games, both to divisional opponents, by a combined four points. The Lions will win this game to improve to 11-1, but Chicago will keep this game close enough to cover the 10.5 points.

New York Giants vs. Dallas Cowboys Odds and Best Bets

The middle game on this year’s Thanksgiving slate is an NFC East matchup between the Giants (2-9) and the Cowboys (4-7). Dallas is a 4.5-point favorite in Bovada’s Thanksgiving NFL lines for Week 13. Both teams have disappointed this season and have been forced to make quarterback changes recently.

Cooper Rush led the Cowboys to an improbable win over the Commanders in Week 12. Despite being the favorite, believing in Rush and company this weekend is challenging. The Cowboys are not just winless at home, all their losses have been blowouts.

New York, on the other hand, looked like a team that did not want to play in their 30-7 loss to the Buccaneers. I think they will be motivated this week against a divisional opponent. Another week of practice should also benefit Tommy DeVito, and I think he will lead the Giants to the upset win on Thanksgiving.

Miami Dolphins vs. Green Bay Packers Odds and Best Bets

The third and final game on this year’s NFL Thanksgiving schedule is a cross-conference matchup between the Dolphins (5-6) and the Packers (8-3). Miami is a 3.5-point road underdog in the latest NFL spreads for Week 13 at offshore sportsbooks.

Playing at Lambeau is a significant advantage for the Packers most weeks already. This week, the cold temperatures in Green Bay will be especially advantageous, as Dolphins’ quarterback Tua Tagovailoa has never won a game when it was below 40 degrees.

It will be cold on Thursday in Green Bay and may even snow at Lambeau. With that in mind, the Packers’ defense should be able to contain the typically explosive Dolphins’ offense. Green Bay wins and covers in this prime-time Thanksgiving Day matchup.

Las Vegas Raiders vs. Kansas City Chiefs Odds and Best Bets

The second-ever NFL Black Friday Game is an AFC West showdown between the Las Vegas Raiders (2-9) and the Kansas City Chiefs (10-1). Bovada lists the Chiefs as a 13.5-point home favorite for this divisional clash. Kansas City is 16-2 in its last 18 games, but one of those losses came against the Raiders on Christmas Day, 2023.

Las Vegas is unlikely to repeat the late-season upset this year, but they could cover the 13.5-point spread. Last week, Kansas City needed a walk-off field goal to beat the Panthers (3-8). Even Patrick Mahomes has expressed frustration about the Chiefs not blowing teams out.

The Chiefs beat the Raiders by a touchdown in their first meeting this season, and I think the outcome will be similar this time. Kansas City wins, but the Raiders cover the 13.5-point spread on Friday.

Los Angeles Chargers vs. Atlanta Falcons Odds and Best Bets

Sunday is also full of exciting matchups, including a cross-conference, cross-country showdown between the Chargers (7-4) and the Falcons (6-5). Atlanta was blown out in Denver before its Week 12 bye, and Los Angeles lost a tough matchup at home to the Ravens on Monday Night Football.

The Falcons need a win to maintain their lead in the NFC South. Bovada lists Atlanta as a 1.5-point home underdog in its current NFL lines for Week 13, 2024. The Falcons have had two weeks to prepare, and their offensive firepower could overwhelm the Chargers’ defense.

LA has the best scoring defense in the NFL, but they also have faced a lot of poor offensive teams this season. Baltimore’s offense had no problem moving the ball against the Chargers, and the Falcons should be similarly successful. Atlanta will pull off the upset this week and retain the top spot in the NFC South.

Pittsburgh Steelers vs. Cincinnati Bengals Odds and Best Bets

Two other teams desperate for wins this week are the Steelers (8-3) and the Bengals (4-7). Pittsburgh requires a win to stay at the top of the AFC North, and Cincinnati would love nothing more than to knock down their divisional rival. The Steelers are 3-point road underdogs in the opening NFL Week 13 lines.

Pittsburgh lost to Cleveland on Thursday Night Football in Week 12. If the Steelers go 0-2 in Ohio, they could also surrender the division lead to the Ravens. Russell Wilson and company must take advantage of Cincinnati’s subpar defense to pull off the upset this week.

The Steelers’ defense also faces an arduous task against Joe Burrow and the Bengals’ offense. Burrow has the third-most passing yards (3,028), second-most passing yards per game (275.3), and is tied for the most passing touchdowns (27) this season. The Bengals have a great offense, but I think the Steelers will bounce back this week and pull off the upset win.

Houston Texans vs. Jacksonville Jaguars Odds and Best Bets

Another divisional matchup on this weekend’s schedule is an AFC South matchup between the Texans (7-5) and the Jaguars (2-9). Houston is a 4.5-point road favorite in Bovada’s early NFL Week 13 projections. The Texans are the top team in the division, but they have stumbled lately.

Houston has lost three of its last four, including a 32-27 loss last week to Tennessee. Jacksonville should be well-rested and recovered from its 52-6 loss to Detroit after its Week 12 bye. Jags’ quarterback Trevor Lawrence is questionable, though, and Jacksonville cannot win this game without him.

Jacksonville has scored just 13 total points in the two games Lawrence has missed. Houston is also desperate to get its season back on track and will be highly motivated for this game. The Texans will win, and assuming Lawrence is out, Houston should cover the 4.5-point spread.

Arizona Cardinals vs. Minnesota Vikings Odds and Best Bets

Arizona (6-5) stumbled in Week 12, losing in Seattle and surrendering the division lead to the Seahawks. Now, the Cardinals face another tough road matchup against the Vikings (9-2) in Minnesota. The Vikings are 3.5-point home favorites in the current NFL Week 13 spreads.

Minnesota battled through Sam Darnold’s midseason slump and is now positioned to win the division and potentially steal the top seed in the NFC if Detroit slips up. Beating Arizona is challenging, but it will be much easier with this game being in Minnesota. The Cardinals are 2-3 on the road, and just 1-2 against the NFC North.

Arizona had won four straight before losing to Seattle, so you cannot count the Cardinals out completely. However, Minnesota should win this game at home to keep pace with the Lions. The Vikings will win on Sunday, but I think the Cardinals are a good bet to cover the 3.5-point spread.

Indianapolis Colts vs. New England Patriots Odds and Best Bets

Indianapolis (5-7) had a chance to close the gap on the Texans with Houston’s loss to the Titans. Anthony Richardson and company could not take advantage of the opportunity, losing 24-6 to the Lions. The good news for the Colts is they face a much more winnable matchup against the Patriots (3-9) this week.

New England is a 3-point home underdog in the current NFL betting lines for Week 13. The Patriots’ offense has looked better with Drake Maye under center, but they have struggled to produce wins. Indy’s defense should have a field day against the rookie quarterback this weekend.

The Colts also have the best offensive player in this game, running back Jonathan Taylor. The fifth-year running back had a rough outing last week, but he will bounce back this week and lead the Colts to cover the spread this week.  

Seattle Seahawks vs. New York Jets Odds and Best Bets

The New York Jets (3-8) have been predictably bad this season in year two of the Aaron Rodgers experiment. While not mathematically eliminated from the postseason yet, the Jets will secure a losing record if they fall short this week. The Jets are 2-point home underdogs to the Seahawks (6-5) in the current NFL Week 13 betting odds.

Seattle claimed the top spot in the NFC West with their 16-6 win over the Cardinals on Sunday. Traveling across the country is tough, but the Seahawks need this win to maintain their lead in a highly competitive division.

New York’s defense has allowed 59 points in its last two games, and Seattle’s Geno Smith leads the NFL in passing YPG (275.9). The Seahawks will win and cover the spread if Smith can continue his high level of play.

Tennessee Titans vs. Washington Commanders Odds and Best Bets

Rookie of the Year favorite Jayden Daniels has struggled mightily recently. The Commanders (7-5) have lost three straight games, and Daniels has thrown for more than 210 yards once in the last four games. Despite their recent struggles, Washington is a 5.5-point home favorite in the NFL odds for Week 13, 2024.

The Commanders host the Titans (3-8), a team that pulled off an improbable win last week. Washington is in a similar slump as Houston. Tennessee caught a struggling Texans’ team at the right time, and they are in a good position to pull off the upset this week.

On the other hand, it is not a good NFL betting strategy to wager on bad quarterbacks to win. Will Levis is one of, if not the, worst quarterbacks in the league. Daniels and the Commanders will bounce back this week, covering the 5.5-point spread against the Titans.

Tampa Bay Buccaneers vs. Carolina Panthers Odds and Best Bets

Tampa Bay (5-6) is within striking distance of Atlanta for the top spot in the NFC South. The Buccaneers can take a major step toward winning the division with a win over the rival Panthers (3-8). Bovada lists Baker Mayfield and company as 6-point road favorites in its Week 13, 2024 NFL odds.

Carolina nearly pulled off the upset over the Chiefs in Week 12, but they could not get the job done. The Panthers have played better since Bryce Young returned to the lineup. However, they will fall short again this week and lose at home to Tampa Bay.

The bigger question is whether the Panthers can cover the 6-point spread. Tampa’s 30-7 win last week ended their four-game losing streak, but the team still has plenty of issues. The Buccaneers will win this game, but I like Carolina to cover as the home underdog.

Los Angeles Rams vs. New Orleans Saints Odds and Best Bets

The Rams could not overcome Saquon Barkley’s MVP-level performance on Sunday Night Football last week. Los Angeles (5-6) can still win its division, but the Rams need a win this week to keep their playoff hopes alive. The Rams are listed as 3-point road favorites this week against the Saints (4-7).

New Orleans won back-to-back games before its Week 12 bye. I think the Saints can build on that momentum this week with an upset win over the Rams.

LA’s offense has struggled to score in two of its last three games, and the Rams’ defense has also been disappointing. The effects of their blowout loss to Philadelphia will linger, and LA will lose again this weekend in New Orleans.

Philadelphia Eagles vs. Baltimore Ravens Odds and Best Bets

Philadelphia (9-2) meets the Ravens (8-4) in Baltimore in a marquee cross-conference matchup this Sunday. The Eagles have won seven straight, but are 3-point underdogs in the NFL football odds for Week 13, 2024. This game will have significant playoff implications and could decide the 2024 MVP race.

Lamar Jackson and Saquon Barkley are two of the top contenders for MVP, and they will both take the field in this game. The Ravens’ defense has been better recently, but it is still one of the worst units in the league this season. Baltimore’s defense will cost them again this week against the Eagles.

Philadelphia’s defense has a tough task this week against Derrick Henry and Jackson. However, I think they will step up to the challenge, and the Eagles will pull off the upset win on the road.

San Francisco 49ers vs. Buffalo Bills Odds and Best Bets

Week 13’s Sunday Night Football matchup pits the 49ers (5-6) against the Bills (9-2) in Buffalo. The Bills are 7-point favorites at home in this cross-conference matchup. San Francisco is desperate for a win, but their chances of securing the upset depending on Brock Purdy’s availability.

The Purdy-less 49ers lost 38-10 in Green Bay last week. San Fran could lose in another blowout this week if Purdy misses another game. The Bills have won six straight and had a bye in Week 12.

Buffalo’s defense has played better than expected this season, and Josh Allen has performed at an MVP level. The Bills offense will move the ball at will if San Fran does not fix its tackling issues from last week. Buffalo will win this prime-time game, and Allen will reinsert himself into the MVP conversation.

Cleveland Browns vs. Denver Broncos Odds and Best Bets

Week 13 concludes with a cross-division matchup between the Browns (3-8) and the Broncos (7-5). Cleveland has already pulled off two improbable upsets this year, beating the Steelers (8-3) and the Ravens (8-4). The Browns are 5.5-point underdogs on the road in Denver for Monday Night Football.

Denver has scored 28 or more points in four of its last six games, and quarterback Bo Nix has played himself into consideration for Rookie of the Year. Cleveland’s defense will be a tough test for Nix, but it is one he will pass. Jameis Winston, on the other hand, is in for a rough night against Denver.

Two of the Browns’ three wins have come against divisional opponents, and their non-division games have largely been blowout losses. That trend will continue this week, with Denver winning convincingly and easily covering the 5.5-point spread. 

Where to Find the Best NFL Betting Lines for Week 13

The early NFL Week 13, 2024 odds are full of exciting betting opportunities. All 32 teams play this weekend, including three Thanksgiving games and a Black Friday game.

Read the guide above to see my NFL Week 13 best bets, then bet on your picks at Bovada. New members can use the code BV1000 during their first deposit to add up to $1,000 to their account. You can also earn prizes for free with our Beat the Geek contest.

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